Company Description

Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle® Drug Conjugate (BDC®) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BDC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist® (Bicycle TICA®) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle® Radioconjugates (BRC®) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle® technology to develop therapies for diseases beyond oncology.

Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, Massachusetts, USA. For more information, visit bicycletherapeutics.com

Culture is key and all Bicycle employees actively embrace and role model our company values:

• We are Adventurous. We believe it’s the way to deliver extraordinary results for our patients.
• We are Dedicated to our Mission. You can’t change the world if you don’t have determination.
• We are One Team. We only succeed when we work together.

Job Description

Based in our purpose-built facility at Granta Park, the role of the Senior Associate, Logistics Management is to drive the operational effectiveness for our global shipping and receiving of goods, maintaining the correct processes from a regulatory perspective, whilst ensuring cost efficiency and performance for the company. This role will build and maintain excellent stakeholder relationships across the company, key external contractors and other third parties, to ensure the timely, efficient and compliant supply chain movements to and from our Portway site and third-party collaborators.

This highly visible role is essential for ensuring a dynamic and adaptable service, that reflects Bicycle’s global ambitions and values. In the pursuit of being the world-class leader in solid tumor medicines, it is key we deliver functions that enable and support our talent and our science.

Specifically, this role will strengthen the experience and knowledge of the Laboratories and Facilities team, reaching out across the organisation to collaborate with diverse areas such as Research and Innovation, Chemistry, Manufacturing, and Controls (CMC) and other internal stakeholders, to deliver the future plans for company growth and Bicycle’s corporate ambitions.

We also aspire to be a leading biotech in the Environment, Health and Safety area, and this role will play a key part working with senior leadership and employees to plan and embed best practice in this sphere.

You will be an excellent communicator, able to build strong relationships, have meaningful interactions with your stakeholders, and have experience of working in a dynamic and fast-paced environment.

• Effective day to day management and performance of logistics throughout the company pipeline, liaising with couriers, internal clients and other third parties, ensuring compliance with applicable laws, regulations and GxP standards.
• Prepare documentation and package shipments for our Research & Innovation teams, both domestic and international, ensuring compliance with all relevant legislation, dangerous goods transport regulations (air/road/sea) and H&S standards.
• Liaise with regulatory agents, customs brokers and other parties to resolve complex queries and blockers for the delivery and import of global shipments.
• Assist management with metrics and KPI information to assess operational and financial performance and advise on future business requirements.
• Create, maintain and update relevant logistics documentation, including SOPs and training documentation, in support of service delivery, compliance and staff training.
• Represent Logistics in local and company-wide meetings, including those involving Environmental, Social and Governance (ESG), Health and Safety, facilities strategy meetings and project meetings requiring specific logistics support.
• Lead continuous improvement initiatives and maintain personal development by keeping up to date with the latest regulations, best practices and perform root cause analysis on logistics issues.
• Raise and approve purchase orders, working with Finance to deal with invoices and queries.
• Create and maintain clear and auditable processes for correct receipting and shipping of goods, including hazardous materials and biological samples in coordination with scientific teams and the Laboratory Support team.
• Assist with the day-to-day upkeep of stocks in inventory stores to ensure continual support of essential science and business practices.
• Ensure maintenance and cleanliness of the spaces used by Logistics and stores.

Performing other occasional tasks fitting this grade and the skill set of the individual may also be required by this role, including backing up for peers during holidays / absence.

Qualifications

Essential:

• Substantial practical and technical knowledge and experience of logistics and shipping within a scientific environment.
• Ability to convey complex technical information in a concise, straightforward manner to non-specialists, to advise on best practice and to produce buy-in for projects and changes.
• Experience of logistics and supply chains in relation to manufacturing pharmaceuticals (e.g. CMC) or hazardous goods.
• Experience of managing internal stakeholders, as well as third-party contractors, couriers, inspection agents, and receivers/shippers.
• Evidence of recent certification in the carriage of dangerous goods e.g. IATA certified.
• Experience in project management and leading process improvement projects.
• Experience of training employees in logistics processes.
• Able to work unsupervised and on own initiative, but with a strong team and service ethic.
• Good competency levels in standard business software packages, including MS Teams, Excel, Word and bespoke platforms such as Oracle based programs.

Desirable:

• Certification of The Carriage of Radioactive Material by Air
• Previous experience as a Dangerous Goods Safety Adviser (DGSA).
• Previous involvement in “Green”/sustainability initiatives within the Logistics area.

Additional Information

• State-of-the-art campus environment with on campus restaurant and Montessori nursery
• Flexible working environment
• Competitive reward including annual company bonus
• Employee recognition schemes
• 28 days annual leave in addition to bank holidays + option to buy up to 5 additional days annually
• Employer contribution to pension (employee does not have to contribute)
• Life assurance cover 4x basic salary
• Private Medical Insurance, including optical and dental cover
• Enhanced parental leave policies
• Group income protection
• Employee assistance program
• Health Cash Plan
• Access to company subsidized gym membership
• Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.
• Cycle to work scheme

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.