About SonoThera:

SonoThera is a venture-backed genetic medicine company advancing ultrasound-mediated, non-viral targeted therapies to unlock the full potential of genetic medicines. Our platform is designed to overcome key limitations in the field, enabling precise, redosable delivery across a broad range of diseases with high unmet need. Headquartered in South San Francisco, SonoThera brings together a world-class, interdisciplinary team focused on translating breakthrough science into transformative therapies.

The Role:

The Gene Therapy group at SonoThera is seeking to hire a Scientist I (temporary) to become an integral part of the gene therapy drug development effort. We seek candidates who think critically and have the desire and ability to learn new techniques. This position requires adaptability and an ability to perform at a high level in a fast-paced environment. The ideal candidate will leverage their mass spectrometry and chromatography expertise to develop assays in support of SonoThera’s gene therapy programs. This is a 7-month full-time contract role.

What You Will Do:

• Develop targeted proteomic assays to support drug product characterization
• Use LC-MS QQQ/QTrap for MRM/SRM analysis (Shimadzu, Agilent, Waters, ExionLC AE, Sciex), including method development, routine instrument maintenance, and troubleshooting
• Analyze quantitative proteomics data using proteomics analysis software (Skyline, SciexOS) and bioinformatics tools for protein and peptide quantification
• Research literature and external sources to identify new techniques and procedures

What You Will Bring:

• Ph.D. with 0-3 years, M.S. with 6+ years, or B.S. with 8+ years of industry experience in analytical chemistry, chemical biology, biochemistry or a related field
• Creativity and the ability to work within an interdisciplinary team to achieve technical and corporate milestones
• Strong verbal and written communication, critical thinking, and problem-solving skills
• Familiarity with ELNs (ie: Benchling)
• Strong record-keeping and organizational skills
• Working knowledge with recombinant protein downstream purification and characterization (nice to have)
• Familiarity with Olink-based proteomics, MSD, Western blot, metabolomics and unbiased proteomics analysis (nice to have)

Compensation: The hourly range for this position is $50 to $60 USD. This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.

Equal Opportunity for Diversity & Inclusion

SonoThera provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.